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Cysticercosis
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==Signs and symptoms== ===Muscles=== Cysticerci can develop in any [[voluntary muscle]]. Invasion of muscle can cause [[myositis|inflammation of the muscle]], with [[fever]], [[eosinophilia]], and [[Muscle hypertrophy|increased size]], which initiates with muscle swelling and later progress to [[atrophy]] and [[fibrosis|scarring]]. In most cases, it is asymptomatic since the cysticerci die and become [[calcification|calcified]].<ref name="test">{{cite book |first1=E.K. |last1=Markell |first2=D.T. |last2=John |first3=W.A. |last3=Krotoski |title=Markell and Voge's medical parasitology |url=https://archive.org/details/markellvogesmedi0000mark_8thed |url-access=registration |year=1999 |publisher=Saunders |isbn=978-0-7216-7634-0 |edition=8th }}</ref> ===Nervous system=== The term [[neurocysticercosis]] is generally accepted to refer to cysts in the [[parenchyma]] of the brain. It presents with seizures and, less commonly, headaches.<ref name="pmid19836788">{{cite journal |vauthors=Kerstein AH, Massey AD |title=Neurocysticercosis |journal=Kansas Journal of Medicine |year=2010 |volume=3 |issue=4 |pages=52β4 |url=http://archie.kumc.edu/handle/2271/867 |url-status=live |archive-url=https://web.archive.org/web/20110719225826/http://archie.kumc.edu/handle/2271/867 |archive-date=2011-07-19 |doi=10.17161/kjm.v3i4.11320 |doi-access=free }}</ref> Cysticerca in brain parenchyma are usually 5β20 mm in diameter. In subarachnoid space and fissures, lesions may be as large as 6 cm in diameter and lobulated. They may be numerous and life-threatening.<ref>{{cite journal|last1=Fleury|first1=A|last2=Dessein|first2=A|last3=Preux|first3=PM|last4=Dumas|first4=M|last5=Tapia|first5=G|last6=Larralde|first6=C|last7=Sciutto|first7=E|s2cid=30854700|title=Symptomatic human neurocysticercosis--age, sex and exposure factors relating with disease heterogeneity.|journal=Journal of Neurology|date=July 2004|volume=251|issue=7|pages=830β7|pmid=15258785|url= http://www.thelancet.com/article/S0140-6736%2813%2960691-1/abstract|doi=10.1007/s00415-004-0437-9}}</ref> Cysts located within the ventricles of the brain can block the outflow of [[cerebrospinal fluid]] and present with symptoms of increased [[intracranial pressure]].<ref>{{cite journal |vauthors=Suri A, Goel RK, Ahmad FU, Vellimana AK, Sharma BS, Mahapatra AK |s2cid=207604470 |title=Transventricular, transaqueductal scope-in-scope endoscopic excision of fourth ventricular neurocysticercosis: a series of 13 cases and a review |journal=J Neurosurg Pediatr |volume=1 |issue=1 |pages=35β9 |date=January 2008 |pmid=18352801 |doi=10.3171/PED-08/01/035 }}</ref> Racemose neurocysticercosis refers to cysts in the [[subarachnoid space]]. These can occasionally grow into large lobulated masses causing pressure on surrounding structures.<ref>{{cite journal |vauthors=Hauptman JS, Hinrichs C, Mele C, Lee HJ |s2cid=21535283 |title=Radiologic manifestations of intraventricular and subarachnoid racemose neurocysticercosis |journal=Emerg Radiol |volume=11 |issue=3 |pages=153β7 |date=April 2005 |pmid=16028320 |doi=10.1007/s10140-004-0383-y}}</ref> Spinal cord neurocysticercosis most commonly presents symptoms such as back pain and [[radiculopathy]].<ref>{{cite journal|vauthors=Jang JW, Lee JK, Lee JH, Seo BR, Kim SH | s2cid=1951568 | title=Recurrent primary spinal subarachnoid neurocysticercosis. | journal=Spine | date=Mar 2010 | volume=35 | issue=5 | pages=E172β5|doi=10.1097/BRS.0b013e3181b9d8b6| pmid=20118838 }}</ref> ===Eyes=== In some cases, cysticerci may be found in the [[globe (human eye)|eyeball]], [[extraocular muscles]], and under the [[conjunctiva]] (''subconjunctiva''). Depending on the location, they may cause visual difficulties that fluctuate with eye position, retinal edema, hemorrhage, a decreased vision or even a visual loss.<ref name="test" /> ===Skin=== {{main|Cysticercosis cutis}} Subcutaneous cysts are in the form of firm, mobile nodules, occurring mainly on the trunk and extremities.<ref name="eight">{{cite journal |author=Wortman PD |title=Subcutaneous cysticercosis |journal=J. Am. Acad. Dermatol. |volume=25 |issue=2 Pt 2 |pages=409β14 |date=August 1991 |pmid=1894783 | doi=10.1016/0190-9622(91)70217-p }}</ref> Subcutaneous nodules are sometimes painful.{{cn|date=May 2021}}
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