Editing Fever Q (section)

== Prevention ==
Prophylactic protection is possible with the use of Q-Vax: a whole-cell, inactivated [[wikipedia:Vaccine|vaccine]] developed by Australian vaccine manufacturer [[wikipedia:CSL Limited|CSL Limited]].<ref name="csl">{{Cite web|url=http://www.csl.com.au/docs/39/836/Q-Vax_PI_V4_TGA-Approved-17%20January%202014.pdf|title=Q&nbsp;fever Vaccine|publisher=CSL|date=17 January 2014|access-date=11 July 2015|url-status=dead|archive-url=https://web.archive.org/web/20170309080855/http://www.csl.com.au/docs/39/836/Q-Vax_PI_V4_TGA-Approved-17%20January%202014.pdf|archive-date=9 March 2017}}</ref> The intradermal vaccination is composed of killed ''C.&nbsp;burnetii'' organisms. Skin and blood tests should be done before vaccination to identify pre-existing immunity, because vaccinating people who already have an immunity can result in a severe local reaction. After a single dose of vaccine, protective immunity lasts for many years. Revaccination is not generally required. Annual screening is typically recommended.<ref>{{cite web |url=http://cdp.ucsf.edu/fileUpload/UCSF_CDP_Q_Fever_Surveillance_Policy_Q_Neg_Wethers.pdf |title=USCF communicable disease prevention program animal exposure surveillance program |access-date=2007-05-08 |url-status=dead |archive-url=https://web.archive.org/web/20070701075855/http://cdp.ucsf.edu/fileUpload/UCSF_CDP_Q_Fever_Surveillance_Policy_Q_Neg_Wethers.pdf |archive-date=2007-07-01 }}</ref>

In 2001, Australia introduced a national Q&nbsp;fever vaccination program for people working in “at risk” occupations. Vaccinated or previously exposed people may have their status recorded on the Australian Q&nbsp;Fever Register,<ref>{{cite web|url=https://www.qfever.org|title=Australian Q Fever Register|publisher=AusVet|access-date=12 February 2016}}</ref> which may be a condition of employment in the meat processing industry or in [[University of Melbourne Faculty of Veterinary and Agricultural Sciences|veterinary research]].<ref>{{Cite web|last=Mckenzie|first=Bex|date=2019-11-20|title=Q-Fever Vaccinations|url=https://fvas.unimelb.edu.au/students/admin/q-fever|access-date=2020-07-11|website=Faculty of Veterinary and Agricultural Sciences|language=en}}</ref> An earlier killed vaccine had been developed in the Soviet Union, but its side effects prevented its licensing abroad.{{citation needed|date=November 2020}}

Preliminary results suggest vaccination of animals may be a method of control. Published trials proved that use of a registered phase vaccine (Coxevac) on infected farms is a tool of major interest to manage or prevent early or late abortion, repeat breeding, [[anoestrus]], silent oestrus, [[metritis]], and decreases in milk yield when ''C.&nbsp;burnetii'' is the major cause of these problems.<ref>{{Cite journal|last1=Camuset|first1=Ph.|last2=Remmy|first2=D.|title= Q&nbsp;Fever (Coxiella Burnetii) Eradication in a Dairy Herd by using Vaccination with a Phase&nbsp;1 Vaccine (Coxevac®, Ceva S.A.)|url=https://www.ivis.org/library/wab/wbc-congress-hungary-2008/q-fever-coxiella-burnetii-eradication-a-dairy-herd-by-using|journal=Proceedings of the XXV Jubilee World Buiatrics Congress|year=2008|pages=80–81|publisher=Magyar Állatorvosol Lapja|location=[[wikipedia:Budapest|Budapest]]|url-access=registration|oclc=324998468}}</ref><ref>{{cite journal|pmid=21392427|year=2011|last1=Hogerwerf|first1=L|last2=Van Den Brom|first2=R|last3=Roest|first3=HI|last4=Bouma|first4=A|last5=Vellema|first5=P|last6=Pieterse|first6=M|last7=Dercksen|first7=D|last8=Nielen|first8=M|title=Reduction of Coxiella burnetii prevalence by vaccination of goats and sheep, the Netherlands| volume=17| issue=3| pages=379–386|doi=10.3201/eid1703.101157|pmc=3166012|journal=Emerging Infectious Diseases}}</ref><!--what is "Wannyn (2007) meant to be?-->