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=== Biological warfare === ''C burnetii'' has been developed as a [[biological agent|biological weapon]].<ref name="pmid14592601">{{cite journal |vauthors=Madariaga MG, Rezai K, Trenholme GM, Weinstein RA |title=Q Fever: A biological weapon in your backyard |journal=Lancet Infect Dis |volume=3 |issue=11 |pages=709β21 |date=November 2003 |pmid=14592601 |doi= 10.1016/S1473-3099(03)00804-1}}</ref> The United States investigated it as a potential biological warfare agent in the 1950s, with eventual standardization as agent OU. At Fort Detrick and Dugway Proving Ground, human trials were conducted on [[Operation Whitecoat|Whitecoat volunteers]] to determine the median infective dose (18 MICLD<sub>50</sub>/person i.h.) and course of infection. The [[Deseret Test Center]] dispensed biological Agent OU with ships and aircraft, during [[Project 112]] and [[Project SHAD]].<ref name="Shady">[http://mcm.fhpr.osd.mil/Librries/CBexposuresDocs/shady_grove_revised.sflb.ashx Deseret Test Center, Project SHAD, Shady Grove revised fact sheet]{{Dead link|date=May 2020 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> As a standardized biological, it was manufactured in large quantities at [[Pine Bluff Arsenal]], with 5,098 gallons in the arsenal in bulk at the time of demilitarization in 1970. ''C. burnetii'' is currently ranked as a "[[Bioterrorism#Types of agents|category B]]" [[bioterrorism]] agent by the [[Centers for Disease Control and Prevention|CDC]].<ref name="pmid12704232">{{cite journal |vauthors=Seshadri R, Paulsen IT, Eisen JA, etal |title=Complete genome sequence of the Q-fever pathogen Coxiella burnetii |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue=9 |pages=5455β60 |date=April 2003 |pmid=12704232 |pmc=154366 |doi=10.1073/pnas.0931379100 |bibcode=2003PNAS..100.5455S }}</ref> It can be contagious, and is very stable in aerosols in a wide range of temperatures. Q fever microorganisms may survive on surfaces up to 60 days. It is considered a good agent in part because its ID<sub>50</sub> (number of bacilli needed to infect 50% of individuals) is considered to be one, making it the lowest known.{{Dubious|date=July 2020|reason=The CDC (https://www.cdc.gov/qfever/transmission/index.html) states that in some cases, fewer than ten bacteria are enough to cause an infection. There is no source here backing up the claim that one is enough 50% of the time.}}
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