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Leptospirosis - Revision history
2026-05-10T07:07:52Z
Revision history for this page on the wiki
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Bloit at 00:07, 30 March 2026
2026-03-30T00:07:26Z
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<a href="https://zoophilia.wiki/index.php?title=Leptospirosis&diff=135105&oldid=134565">Show changes</a>
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Niggtard at 19:15, 26 March 2026
2026-03-26T19:15:46Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:15, 26 March 2026</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGERNIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER NIGGER ==</div></td></tr>
</table>
Niggtard
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=134557&oldid=prev
Dnbcobsongrapsit at 19:10, 26 March 2026
2026-03-26T19:10:39Z
<p></p>
<a href="https://zoophilia.wiki/index.php?title=Leptospirosis&diff=134557&oldid=134468">Show changes</a>
Dnbcobsongrapsit
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=134468&oldid=prev
Goonson at 18:39, 26 March 2026
2026-03-26T18:39:27Z
<p></p>
<a href="https://zoophilia.wiki/index.php?title=Leptospirosis&diff=134468&oldid=133510">Show changes</a>
Goonson
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=133510&oldid=prev
Rauhbautz at 20:41, 15 October 2024
2024-10-15T20:41:37Z
<p></p>
<a href="https://zoophilia.wiki/index.php?title=Leptospirosis&diff=133510&oldid=130604">Show changes</a>
Rauhbautz
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=130604&oldid=prev
ZooWiki: The LinkTitles extension automatically added links to existing pages (<a rel="nofollow" class="external free" href="https://github.com/bovender/LinkTitles">https://github.com/bovender/LinkTitles</a>).
2021-06-14T20:17:14Z
<p>The LinkTitles extension automatically added links to existing pages (<a rel="nofollow" class="external free" href="https://github.com/bovender/LinkTitles">https://github.com/bovender/LinkTitles</a>).</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:17, 14 June 2021</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l50">Line 50:</td>
<td colspan="2" class="diff-lineno">Line 50:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Through [[innate immune system]], endothelial cells of the capillaries in the human body are activated by the presence of these bacteria. The endothelial cells produce [[cytokines]] and [[antimicrobial peptides]] against the bacteria. These products regulate the [[Coagulation#Coagulation cascade|coagulation cascade]] and movements of white blood cells.<ref name=Picardeau2017/> Macrophages presented in humans are able to [[phagocytose|engulf]] ''Leptospira''. However, ''Leptospira'' are able to reside and proliferate in the [[cytosol|cytoplasmic matrix]] after being ingested by macrophages.<ref name=Picardeau2017/> Those with severe leptospirosis can experience a high level of cytokines such as [[interleukin 6]], [[tumor necrosis factor alpha]] (TNF-α), and [[interleukin 10]]. The high level of cytokines causes [[sepsis]]-like symptoms which is life-threatening instead of helping to fight against the infection.<ref name="Cagliero 2018"/> Those who have a high risk of sepsis during a leptospirosis infection are found to have the [[HLA-DQ6]] [[genotype]], possibly due to [[superantigen]] activation, which damages bodily organs.<ref name="Haake 2015"/></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Through [[innate immune system]], endothelial cells of the capillaries in the human body are activated by the presence of these bacteria. The endothelial cells produce [[cytokines]] and [[antimicrobial peptides]] against the bacteria. These products regulate the [[Coagulation#Coagulation cascade|coagulation cascade]] and movements of white blood cells.<ref name=Picardeau2017/> Macrophages presented in humans are able to [[phagocytose|engulf]] ''Leptospira''. However, ''Leptospira'' are able to reside and proliferate in the [[cytosol|cytoplasmic matrix]] after being ingested by macrophages.<ref name=Picardeau2017/> Those with severe leptospirosis can experience a high level of cytokines such as [[interleukin 6]], [[tumor necrosis factor alpha]] (TNF-α), and [[interleukin 10]]. The high level of cytokines causes [[sepsis]]-like symptoms which is life-threatening instead of helping to fight against the infection.<ref name="Cagliero 2018"/> Those who have a high risk of sepsis during a leptospirosis infection are found to have the [[HLA-DQ6]] [[genotype]], possibly due to [[superantigen]] activation, which damages bodily organs.<ref name="Haake 2015"/></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[Humoral immunity]] is the main immune response against the ''Leptospira'' cells. Agglutinating antibodies such as [[immunoglobulin M]] and [[immunoglobulin G]] are produced against the bacteria. Such antibodies are mainly directed against the [[lipopolysaccharide|LPS]].<ref name="Kin Chin 2019"/> ''Leptospira'' LPS only activates [[toll-like receptor 2]] (TLR2) in [[monocyte]]s in humans. The lipid A molecule of the bacteria is not recognised by human [[TLR4]] receptors. Therefore, the lack of ''Leptospira'' recognition by TLR4 receptors probably contributes to the leptospirosis disease process in humans.<ref name=Picardeau2017/></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[Humoral immunity]] is the <ins style="font-weight: bold; text-decoration: none;">[[Portal:Main|</ins>main<ins style="font-weight: bold; text-decoration: none;">]] </ins>immune response against the ''Leptospira'' cells. Agglutinating antibodies such as [[immunoglobulin M]] and [[immunoglobulin G]] are produced against the bacteria. Such antibodies are mainly directed against the [[lipopolysaccharide|LPS]].<ref name="Kin Chin 2019"/> ''Leptospira'' LPS only activates [[toll-like receptor 2]] (TLR2) in [[monocyte]]s in humans. The lipid A molecule of the bacteria is not recognised by human [[TLR4]] receptors. Therefore, the lack of ''Leptospira'' recognition by TLR4 receptors probably contributes to the leptospirosis disease process in humans.<ref name=Picardeau2017/></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Although there are various mechanisms in the human body to fight against the bacteria, ''Leptospira'' is well adapted to such an inflammatory condition created by it.<!-- <ref name=Picardeau2017/> --> In the bloodstream, it can activate host plasminogen to become [[plasmin]] that breaks down extracellular matrix, degrades [[fibrin]] clots and complemental proteins ([[C3b]] and [[Complement component 5|C5]]) to avoid [[opsonisation]]. It can also recruit complement regulators such as [[Factor H]], [[Complement component 4B|C4b]]-binding protein, factor H-like binding protein, and [[vitronectin]] to prevent the activation of [[Complement membrane attack complex|membrane attack complex]] on its surface. It also secretes [[protease]]s to degrade complement proteins such as [[Complement component 3|C3]]. It can bind to thrombin that decreases the fibrin formation. Reduced fibrin formation increases the risk of bleeding.<ref name=Picardeau2017/> ''Leptospira'' also secretes [[sphingomyelinase]] and [[haemolysin]] that target red blood cells.<ref name="Karpagm2020"/></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Although there are various mechanisms in the human body to fight against the bacteria, ''Leptospira'' is well adapted to such an inflammatory condition created by it.<!-- <ref name=Picardeau2017/> --> In the bloodstream, it can activate host plasminogen to become [[plasmin]] that breaks down extracellular matrix, degrades [[fibrin]] clots and complemental proteins ([[C3b]] and [[Complement component 5|C5]]) to avoid [[opsonisation]]. It can also recruit complement regulators such as [[Factor H]], [[Complement component 4B|C4b]]-binding protein, factor H-like binding protein, and [[vitronectin]] to prevent the activation of [[Complement membrane attack complex|membrane attack complex]] on its surface. It also secretes [[protease]]s to degrade complement proteins such as [[Complement component 3|C3]]. It can bind to thrombin that decreases the fibrin formation. Reduced fibrin formation increases the risk of bleeding.<ref name=Picardeau2017/> ''Leptospira'' also secretes [[sphingomyelinase]] and [[haemolysin]] that target red blood cells.<ref name="Karpagm2020"/></div></td></tr>
</table>
ZooWiki
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=129959&oldid=prev
ZooWiki: The LinkTitles extension automatically added links to existing pages (<a rel="nofollow" class="external free" href="https://github.com/bovender/LinkTitles">https://github.com/bovender/LinkTitles</a>).
2021-06-07T16:33:05Z
<p>The LinkTitles extension automatically added links to existing pages (<a rel="nofollow" class="external free" href="https://github.com/bovender/LinkTitles">https://github.com/bovender/LinkTitles</a>).</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:33, 7 June 2021</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l93">Line 93:</td>
<td colspan="2" class="diff-lineno">Line 93:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Treatment==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Treatment==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Most leptospiral cases resolve spontaneously. Early initiation of antibiotics may prevent the progression to severe disease. Therefore, in resource-limited settings, antibiotics can be started once leptospirosis is suspected after history taking and examination.<ref name="Haake 2015"/></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Most leptospiral cases resolve spontaneously. Early initiation of antibiotics may prevent the progression to severe disease. Therefore, in resource-limited settings, antibiotics can be started once leptospirosis is suspected after <ins style="font-weight: bold; text-decoration: none;">[[</ins>history<ins style="font-weight: bold; text-decoration: none;">]] </ins>taking and examination.<ref name="Haake 2015"/></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>For mild leptospirosis, antibiotic recommendations such as doxycycline, [[azithromycin]], [[ampicillin]] and [[amoxicillin]] were based solely on ''in vitro'' testing.<ref name="Lane 2016"/> In 2001, the WHO recommended oral doxycycline (2&nbsp;mg/kg up to 100&nbsp;mg every 12&nbsp;hours) for five to seven days for those with mild leptospirosis. [[Tetracycline]], ampicillin, and amoxicillin can also be used in such cases.<ref name="WHO"/> However, in areas where [[rickettsia]] and leptospirosis are both endemic, azithromycin and doxycycline are the drugs of choice.<ref name="Lane 2016"/></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>For mild leptospirosis, antibiotic recommendations such as doxycycline, [[azithromycin]], [[ampicillin]] and [[amoxicillin]] were based solely on ''in vitro'' testing.<ref name="Lane 2016"/> In 2001, the WHO recommended oral doxycycline (2&nbsp;mg/kg up to 100&nbsp;mg every 12&nbsp;hours) for five to seven days for those with mild leptospirosis. [[Tetracycline]], ampicillin, and amoxicillin can also be used in such cases.<ref name="WHO"/> However, in areas where [[rickettsia]] and leptospirosis are both endemic, azithromycin and doxycycline are the drugs of choice.<ref name="Lane 2016"/></div></td></tr>
</table>
ZooWiki
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=129055&oldid=prev
Quantumhusky at 05:08, 6 June 2021
2021-06-06T05:08:35Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 05:08, 6 June 2021</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Prevention==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Prevention==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File:A Leptospirosis warning notice board.jpg|thumb|alt=A sign warning against swimming in a lake with pathogenic Leptospira in Sarawak, Malaysia. | A notice board by a lakeside in [[Sarawak]], Malaysia that warns against swimming in the lake as it has tested positive for pathogenic ''Leptospira''.]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File:A Leptospirosis warning notice board.jpg|thumb|alt=A sign warning against swimming in a lake with pathogenic Leptospira in Sarawak, Malaysia. | A notice board by a lakeside in [[Sarawak]], Malaysia that warns against swimming in the lake as it has tested positive for pathogenic ''Leptospira''.]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[File:Capture.<del style="font-weight: bold; text-decoration: none;">jpg</del>|thumb|alt=Blood samples being taken from several men| Blood samples being taken from a group of residents in [[Boyolali Regency]], Indonesia for leptospirosis screening tests.]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[File:Capture.<ins style="font-weight: bold; text-decoration: none;">png</ins>|thumb|alt=Blood samples being taken from several men| Blood samples being taken from a group of residents in [[Boyolali Regency]], Indonesia for leptospirosis screening tests.]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Rates of leptospirosis can be reduced by improving housing, infrastructure, and sanitation standards. Rodent abatement efforts and flood mitigation projects can also help to prevent it.<ref name="Haake 2015"/> Proper use of [[personal protective equipment]] (PPE) by people who have a high risk of occupational exposure can prevent leptospirosis infections in most cases.<ref name="Haake 2015"/></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Rates of leptospirosis can be reduced by improving housing, infrastructure, and sanitation standards. Rodent abatement efforts and flood mitigation projects can also help to prevent it.<ref name="Haake 2015"/> Proper use of [[personal protective equipment]] (PPE) by people who have a high risk of occupational exposure can prevent leptospirosis infections in most cases.<ref name="Haake 2015"/></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
</table>
Quantumhusky
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=129054&oldid=prev
Quantumhusky at 05:08, 6 June 2021
2021-06-06T05:08:02Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 05:08, 6 June 2021</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Prevention==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Prevention==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File:A Leptospirosis warning notice board.jpg|thumb|alt=A sign warning against swimming in a lake with pathogenic Leptospira in Sarawak, Malaysia. | A notice board by a lakeside in [[Sarawak]], Malaysia that warns against swimming in the lake as it has tested positive for pathogenic ''Leptospira''.]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[File:A Leptospirosis warning notice board.jpg|thumb|alt=A sign warning against swimming in a lake with pathogenic Leptospira in Sarawak, Malaysia. | A notice board by a lakeside in [[Sarawak]], Malaysia that warns against swimming in the lake as it has tested positive for pathogenic ''Leptospira''.]]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[[File:<del style="font-weight: bold; text-decoration: none;">Leptospirosis screening in Indonesia</del>.<del style="font-weight: bold; text-decoration: none;">png</del>|thumb|alt=Blood samples being taken from several men| Blood samples being taken from a group of residents in [[Boyolali Regency]], Indonesia for leptospirosis screening tests.]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[[File:<ins style="font-weight: bold; text-decoration: none;">Capture</ins>.<ins style="font-weight: bold; text-decoration: none;">jpg</ins>|thumb|alt=Blood samples being taken from several men| Blood samples being taken from a group of residents in [[Boyolali Regency]], Indonesia for leptospirosis screening tests.]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Rates of leptospirosis can be reduced by improving housing, infrastructure, and sanitation standards. Rodent abatement efforts and flood mitigation projects can also help to prevent it.<ref name="Haake 2015"/> Proper use of [[personal protective equipment]] (PPE) by people who have a high risk of occupational exposure can prevent leptospirosis infections in most cases.<ref name="Haake 2015"/></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Rates of leptospirosis can be reduced by improving housing, infrastructure, and sanitation standards. Rodent abatement efforts and flood mitigation projects can also help to prevent it.<ref name="Haake 2015"/> Proper use of [[personal protective equipment]] (PPE) by people who have a high risk of occupational exposure can prevent leptospirosis infections in most cases.<ref name="Haake 2015"/></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
</table>
Quantumhusky
https://zoophilia.wiki/index.php?title=Leptospirosis&diff=129047&oldid=prev
Quantumhusky at 04:56, 6 June 2021
2021-06-06T04:56:40Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:56, 6 June 2021</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{imported|Wikipedia}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{imported|Wikipedia}}</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{Use dmy dates|date=December 2019}}</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{Use British English|date=March 2020}}</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{short description|Human disease caused by Leptospira bacteria}}</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">{{</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| name = Leptospirosis</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| synonyms = Rat fever,<ref>{{cite book|last1=Berger |first1= Stephen | name-list-style = vanc |title=Leptospirosis: Global Status |date=2018 |publisher=GIDEON Informatics Inc |isbn=9781498820318 |page=7 |url=https://books.google.com/books?id=ekBLDwAAQBAJ&pg=PA7 |language=en}}</ref> field fever,<ref name=Mos2013>{{cite book|title=Mosby's Medical Dictionary|year=2013|publisher=[[Elsevier Health Sciences]]|isbn=9780323112581|page=697|url=https://books.google.com/books?id=aW0zkZl0JgQC&pg=PA697|edition=9|access-date=21 February 2016|archive-url=https://web.archive.org/web/20170908221631/https://books.google.com/books?id=aW0zkZl0JgQC&pg=PA697|archive-date=8 September 2017|url-status=live}}</ref> rat catcher's yellows,<ref name=Mckay2001>{{cite book|last=McKay|first=James E. | name-list-style = vanc |title=Comprehensive Health Care for Dogs|year=2001|publisher=[[The Quarto Group|Creative Pub. International]]|location=Minnetonka, MN.|isbn=9781559717830|page=97}}</ref> pretibial fever<ref name="Andrews">{{cite book| first1 = William D | last1 = James | first2 = Dirk M | last2 = Elston | first3 = Timothy G | last3 = Berger | first4 = George Clinton | last4 = Andrews | name-list-style = vanc |title=Andrews' Diseases of the Skin: Clinical Dermatology |publisher=[[Saunders (imprint)|Saunders Elsevier]] |year=2006 |isbn=978-0-7216-2921-6 }}{{rp|290}}</ref></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| image = Leptospirosis darkfield.jpg</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| alt = </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| caption = ''Leptospira'' magnified 200-fold with a [[dark-field microscope]].</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| <!-- altcaption = A magnified image of Leptospira --></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| field = [[Infectious disease (medical specialty)|Infectious disease]]</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| symptoms = None, [[headache]]s, [[Myalgia|muscle pains]], [[fever]]s<ref name="Zoey2020"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| complications = [[pulmonary haemorrhage|Bleeding from the lungs]], [[meningitis]], [[kidney failure]]<ref name="Zoey2020"/><ref name=McB2005>{{cite journal | vauthors = McBride AJ, Athanazio DA, Reis MG, Ko AI | title = Leptospirosis | journal = Current Opinion in Infectious Diseases | volume = 18 | issue = 5 | pages = 376–86 | date = October 2005 | pmid = 16148523 | doi = 10.1097/01.qco.0000178824.05715.2c | s2cid = 220576544 }}</ref></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| onset = One to two weeks<ref name="Karpagm2020"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| duration = </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| types = </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| causes = ''[[Leptospira]]'' typically spread by [[rodents]]<ref name="Lane 2016"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| risks = Exposure to infected animals or contaminated water<ref name="Lane 2016"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| diagnosis = Testing blood for [[antibodies]] against the bacterium or its [[DNA]]<ref name="Zoey2020"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| differential = [[Malaria]], [[enteric fever]], [[rickettsiosis]], [[dengue]]<ref>{{cite book|last1=Farrar|first1=Jeremy|last2=Hotez|first2=Peter|last3=Junghanss|first3=Thomas|last4=Kang|first4=Gagandeep|last5=Lalloo|first5=David|last6=White|first6=Nicholas J. | name-list-style = vanc |title=Manson's Tropical Diseases E-Book|date=2013|publisher=Elsevier Health Sciences|isbn=9780702053061|page=438|url=https://books.google.com/books?id=GTjRAQAAQBAJ&pg=PA438|language=en|access-date=2 September 2017|archive-url=https://web.archive.org/web/20170908221631/https://books.google.com/books?id=GTjRAQAAQBAJ&pg=PA438|archive-date=8 September 2017|url-status=live}}</ref></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| prevention = [[Personal protective equipment]], hygiene measures, [[doxycycline]]<ref name="Karpagm2020"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| treatment = [[Doxycycline]], [[penicillin]], [[ceftriaxone]]<ref name="Lane 2016"/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| medication = </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| prognosis = Risk of death ~7.5%<ref name="Evangelista2010" /></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| frequency = One million people per year<ref name=Karpagm2020/><ref name=Costa2015/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">| deaths = 58,900 per year<ref name=Costa2015/></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">}}</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><!-- Definition and symptoms --></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><!-- Definition and symptoms --></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Leptospirosis''' is a [[blood infection]] caused by the bacteria ''[[Leptospira]]''.<ref name="Lane 2016"/> Signs and symptoms can range from none to mild ([[headache]]s, [[Myalgia|muscle pains]], and [[fever]]s) to severe ([[pulmonary hemorrhage|bleeding in the lungs]] or [[meningitis]]).<ref name="Zoey2020">{{cite journal | vauthors = Soo ZM, Khan NA, Siddiqui R | title = Leptospirosis: Increasing importance in developing countries | journal = Acta Tropica | volume = 201 | pages = 105183 | date = January 2020 | pmid = 31542372 | doi = 10.1016/j.actatropica.2019.105183 | doi-access = free }}</ref> '''Weil's disease''', the acute, severe form of leptospirosis, causes the infected individual to become [[jaundice]]d (skin and eyes become yellow), develop [[kidney failure]], and bleed.<ref name=McB2005/> Bleeding from the lungs associated with leptospirosis is known as '''"severe pulmonary haemorrhage syndrome"'''.<ref name="Zoey2020"/></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Leptospirosis''' is a [[blood infection]] caused by the bacteria ''[[Leptospira]]''.<ref name="Lane 2016"/> Signs and symptoms can range from none to mild ([[headache]]s, [[Myalgia|muscle pains]], and [[fever]]s) to severe ([[pulmonary hemorrhage|bleeding in the lungs]] or [[meningitis]]).<ref name="Zoey2020">{{cite journal | vauthors = Soo ZM, Khan NA, Siddiqui R | title = Leptospirosis: Increasing importance in developing countries | journal = Acta Tropica | volume = 201 | pages = 105183 | date = January 2020 | pmid = 31542372 | doi = 10.1016/j.actatropica.2019.105183 | doi-access = free }}</ref> '''Weil's disease''', the acute, severe form of leptospirosis, causes the infected individual to become [[jaundice]]d (skin and eyes become yellow), develop [[kidney failure]], and bleed.<ref name=McB2005/> Bleeding from the lungs associated with leptospirosis is known as '''"severe pulmonary haemorrhage syndrome"'''.<ref name="Zoey2020"/></div></td></tr>
</table>
Quantumhusky